Author: Eric Fung
Publisher: Humana Pre
Keywords: methods, biology, molecular, protocols, protein, arrays
Number of Pages: 304
Published: 2004-04-09
List price: $99.50
ISBN-10: 158829255X
ISBN-13: 9781588292551

A diverse collection of unique methodologies to synthesize and construct protein arrays for basic and clinical research in a high-throughput manner. These readily reproducible techniques can be applied to such applications as quantifying specific proteins of interest and discovering novel proteins, as well as to a variety of affinity substances, including antibodies, peptides, proteins, aptamers, and chemicals. The techniques can be used for biomarkers discovery, assay development, clinical sample testing, and building the next generation of molecular tools.

Author: Andrew R. Colli
Publisher: Humana Pre
Keywords: methods, molecular, biology, applications, analysis, disequilibrium, association, mapping, linkage
Number of Pages: 255
Published: 2007-08-23
List price: $99.50
ISBN-10: 1588296695
ISBN-13: 9781588296696

As researchers continue to make enormous progress in mapping disease genes, exciting, novel, and complex analyses have emerged. In Linkage Disequilibrium and Association Mapping: Analysis and Applications, scientists from around the world, who are leaders in this field, contribute their vast experience and expertise to produce a comprehensive and fascinating text for researchers and clinicians alike. The volume comprises four general sections: the first presents an overview and historical basis of the subject. The second section considers the developing methodology and recent findings from stu

Author: Federico Innocenti
Publisher: Humana Pre
Keywords: drug, development, cancer, discovery, response, clinical, pharmacogenomics, genomics, anticancer
Number of Pages: 378
Published: 2008-10-23
List price: $159.00
ISBN-10: 1588296466
ISBN-13: 9781588296467

The availability of new molecular approaches to the selection of drug therapy is an emerging need, as the traditional approach based on the evaluation of patient and tumor characteristics is clearly far from optimal. Many, and in most cases the majority of treated patients do not have significant benefits from the treatment while they often experience moderate to severe toxicities. In “Pharmacogenomics, Anticancer Drug Discovery, and Response”, edited by Federico Innocenti, readers will find a series of chapters addressing the role of genomic information in cancer therapy and in

Author: Alexander Serganov
Publisher: Humana Pre
Keywords: methods, biology, molecular, protocols, riboswitches
Number of Pages: 366
Published: 2009-04-17
List price: $110.00
ISBN-10: 1934115886
ISBN-13: 9781934115886

The revolutionary discoveries of RNA interference and bacterial regulatory RNAs led to further breakthroughs such as the identification of riboswitches and related RNA sensors, mRNA regions capable of alternating their conformations in response to the presence of cellular metabolites and other physical or chemical cues. In "Riboswitches: Methods and Protocols", expert researchers provide comprehensive and up-to-date coverage of various methods used to study riboswitches and other RNAs involved in gene expression control. Examining biochemical and modern biophysical techniques, the volume focus

Author: Vassil St. Georgiev
Publisher: Humana Pre
Keywords: disease, infectious, infections, opportunistic
Number of Pages: 568
Published: 2001-12-15
List price: $135.00
ISBN-10: 1588290093
ISBN-13: 9781588290090

National Institutes of Health, Bethesda, MD. Text designed to provide guidance for clinicians in caring for patients with an underlying immunodeficiency that evolve into opportunistic infections. Emphasizes therapies new to drug development and covers all the major bacterial, viral, parasitic, and fungal infections.

Author: Ann O. Sperry
Publisher: Humana Pre
Keywords: molecular, methods, biology, protocols, motors
Number of Pages: 252
Published: 2007-06-13
List price: $109.00
ISBN-10: 1588296652
ISBN-13: 9781588296658

Molecular motor proteins comprise three protein superfamilies: kinesins, dyneins and myosins. Together, these proteins produce force for movement in an incredibly wide variety of cellular processes including vesicular transport, cell division, nuclear migration, muscle contraction, mechanochemical transduction, among others. In addition, molecular motors are expressed in both simple eukaryotes and in a tissue specific manner in higher cells. This methods volume explores the extreme functional and structural diversity of molecular motors and presents methods relevant to each motor family. In ad

Authors:Charles N. Serhan, Peter A. Ward,
Publisher: Humana Pre
Keywords: inflammation, current, research, basis, cellular, molecular
Number of Pages: 352
Published: 1998-12-09
List price: $150.00
ISBN-10: 0896035956
ISBN-13: 9780896035959

Harvard Medical School, Boston, MA. Reviews current research in the field of inflammation. Addresses: endothelial cell activation, angiogenesis, arachidonic acid cascade, and more. For researchers. DNLM: Inflammation--immunology.