中文参考译名:药物代谢药物设计与开发
Authors:Donglu Zhang, Mingshe Zhu, William G. Humphrey,
Publisher: Wiley-Interscience
Keywords: drug, development, metabolism, design
Number of Pages: 609
Published: 2007-11-09
List price: $130.00
ISBN-10: 047173313X
ISBN-13: 9780471733133
The essentials of drug metabolism vital to developing new therapeutic entities. Information on the metabolism and disposition of candidate drugs is a critical part of all aspects of the drug discovery and development process. Drug metabolism, as practiced in the pharmaceutical industry today, is a complex, multidisciplinary field that requires knowledge of sophisticated analytical technologies and expertise in mechanistic and knowledge of sophisticated analytical technologies and expertise in mechanistic and kinetic enzymology, organic reaction mechanism, pharmacokinetic analysis, animal physi
中文参考译名:药物毒代动力学（药物和化学品毒理学）
Author: Welling
Publisher: Informa Healthcare
Keywords: drug, toxicology, toxicokinetics, chemical
Number of Pages: 432
Published: 1993-05-13
List price: $229.95
ISBN-10: 0824790197
ISBN-13: 9780824790196
This reference/text examines the importance of toxicokinetics on drug disposition and outlines its practical applications in drug development - helping readers incorporate the most up-to-date findings into their own work.;Consolidating research from international authorities in the fields of toxicology, pharmacokinetics, metabolism and biochemistry to illustrate the interdisciplinary nature of toxicokinetic situations, Drug Toxicokinetics: covers regulatory guidelines for conducting toxicokinetic studies to obtain maximum information for safety assessment and clinical use of drug candidates; i
中文参考译名:毒品走私毒品走私：从内部教训
Authors:Scott H. Decker, Margaret Townsend Chapma,
Publisher: Temple University Pre
Keywords: drug, inside, lessons, smuggling, smugglers
Number of Pages: 224
Published: 2008-01-28
List price: $23.95
ISBN-10: 1592136435
ISBN-13: 9781592136438
Drug Smugglers on Drug Smuggling examines the organizational structures of drug smuggling from Colombia to the US. Career drug smugglers describe a series of often disconnected networks that enable smugglers to best organize their business in a way that will minimize the risks of apprhension and maximize profits. Book DescriptionDrug Smugglers on Drug Smuggling features interviews with 34 convicted drug smugglers -- most of them once major operators -- detailing exactly how drugs are smuggled into the U.S. from Latin America. These sources provide tangible evidence of the risks, rewards, and o
中文参考译名:成像在新药研究和早期临床试验（药物研究进展/ Fortschritte德Arneimittelforschung）
Author: Markus Rudi
Publisher: Birkhäuser Basel
Keywords: drug, fortschritte, der, arneimittelforschung, research, trials, discovery, clinical, imaging, progress
Number of Pages: 392
Published: 2005-12-05
List price: $249.00
ISBN-10: 3764371579
ISBN-13: 9783764371579
In this monograph the contribution of imaging modalities to the various stages of drug discovery and development, from early target validation to their use in clinical development programs, is described. Chapters are devoted to the description of the drug discovery process as such, to the various imaging modalities being used both preclinically and clinically, to applications of imaging during the optimization of a lead compound (addressing issues such as bioavailability and efficacy) and during the drug safety evaluation. A chapter describes imaging biomarkers, their development, advantages a
Drug-Drug Interactions: Scientific and Regulatory Perspectives, Volume 43 (Advances in Pharmacology)
中文参考译名:药物相互作用：科学和管理的观点，在药理学43卷（进展）
Authors:Albert P. Li, J. Thomas August, Ferid Murad, M. W.
Publisher: Academic Pre
Keywords: drug, advances, pharmacology, volume, regulatory, interactions, scientific, perspectives
Number of Pages: 304
Published: 1997-10-16
List price: $234.00
ISBN-10: 0120329441
ISBN-13: 9780120329441
Drug-Drug Interactions is a comprehensive review of the scientific and regulatory perspectives of drug-drug interactions from the point-of-view of academia, industry, and government regulatory agencies. This book is intended for professionals in the pharmaceutical industry, health care, and governmental regulatory agencies. Topics of interest include the mechanistic understanding of drug-drug interactions, the prediction of drug-drug interaction potential of new drugs, and the avoidance of clinically significant drug-drug interaction in patients. Key Features* Provides useful references on the
中文参考译名:药物释放：原理与应用（威利系列）在新药研究与发展
Authors:Binghe Wang, Teruna J. Siahaan, Richard A. Soltero
Publisher: Wiley-Interscience
Keywords: drug, discovery, development, series, applications, delivery, principles, wiley
Number of Pages: 464
Published: 2005-03-28
List price: $125.00
ISBN-10: 0471474894
ISBN-13: 9780471474890
An indispensable tool for those working at the front lines of new drug development Written for busy professionals at the forefront of new drug development, Drug Delivery gets readers quickly up to speed on both the principles and latest applications in the increasingly important field of drug delivery. Recent developments in such areas as combinatorial chemistry, proteomics, and genomics have revolutionized researchers’ ability to rapidly identify and synthesize new pharmacological compounds. However, delivery-related properties remain a significant reason for clinical trial failures. Br
中文参考译名:优化“样药”属性的信息（生物技术：药物方面）在药物发现
Authors:Ronald Borchardt, Edward Kerns, Michael Hageman, D
Publisher: Springer
Keywords: drug, pharmaceutical, aspects, biotechnology, leads, properties, optimizing, discovery
Number of Pages: 512
Published: 2006-08-03
List price: $229.00
ISBN-10: 0387340564
ISBN-13: 9780387340562
Traditionally, incorporating optimal drug-like properties into a structural lead was not considered by medicinal chemists to be their responsibility. Instead, medicinal chemists felt that the undesirable drug-like properties in their drug candidates would be fixed by preclinical development scientists. However, that view has changed in the past 5–10 years, resulting in another significant paradigm shift in drug discovery. The most significant aspect of this latest paradigm shift is the recognition by medicinal chemists that the drug-like properties of structural hits, structural leads, and d
